We’ve talked about NAD+ before — but this episode goes deeper. While EP 03 covered the basics, here we zoom out to examine the bigger picture: how NAD+ decline connects to the hallmarks of aging, what the latest lifespan research in humans actually shows, and whether boosting NAD+ could genuinely add years to your life or just dollars to supplement companies’ pockets.
At Zenova Wellness, we hold every claim to a higher standard. Tune in for the full NAD+ story — hype, science, and everything in between.
🎯 Enjoyed this episode? Try next: EP 07: Intermittent Fasting — Science vs. Headlines
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Frequently Asked Questions
How does NAD+ decline connect to the aging process?
NAD+ levels drop by roughly 50% between ages 40 and 60. This decline impairs mitochondrial function, reduces the activity of sirtuins (longevity-associated proteins), and compromises DNA repair capacity — all hallmarks of biological aging.
Can boosting NAD+ actually extend lifespan?
Animal studies have shown lifespan extension with NAD+ precursor supplementation, but robust human lifespan data does not yet exist. Current human trials focus on healthspan markers like muscle function, metabolic health, and cognitive performance.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
What is the recommended dosage of NMN for NAD+ support?
Human trials have used doses ranging from 250 mg to 1,200 mg of NMN daily, with most showing tolerability and NAD+ elevation at 500 mg/day. Optimal dosing is still being studied. Always consult a qualified healthcare provider before starting NMN supplementation.
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